Chromium
A blood test that measures chromium levels to assess this trace element's role in glucose metabolism and nutritional status.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
What this test measures
This test measures the concentration of chromium in blood serum or whole blood. Chromium is a trace mineral that plays a role in glucose metabolism by enhancing the action of insulin, the hormone responsible for moving glucose from the bloodstream into cells. Without adequate chromium, insulin's effectiveness may be reduced, potentially leading to impaired glucose regulation.
Chromium's exact mechanism in the body is still an area of active research, and clinical deficiency in healthy populations consuming a normal diet has not been clearly documented. The test is most commonly ordered when evaluating possible chromium deficiency in individuals with unexplained glucose regulation difficulties, in patients receiving long-term parenteral nutrition (IV feeding), or when assessing potential chromium overexposure in occupational settings where chromium compounds are used industrially.
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Individuals with diabetes or prediabetes who may benefit from understanding their chromium status, as this mineral is involved in glucose metabolism and insulin function.
- Patients receiving long-term intravenous feeding (total parenteral nutrition) who may be at risk for chromium deficiency due to inadequate supplementation in their nutrition solutions.
- Those with symptoms suggestive of glucose intolerance, such as unexplained weight loss, fatigue, or blood sugar irregularities that might be related to chromium status.
- People with metal-on-metal orthopedic implants who need monitoring for elevated chromium levels that could indicate implant wear or toxicity.
- Individuals with suspected chromium toxicity from occupational or environmental exposure who require assessment of their chromium burden.
- Patients with metabolic syndrome or insulin resistance who are exploring nutritional factors that may contribute to their condition.
What to expect
Preparation
No fasting is required for this test. Patients should inform their healthcare provider about any supplements containing chromium or recent exposure to contrast media, as these may affect results.
Sample Type
A blood sample is collected through a simple blood draw from a vein in the arm. Special metal-free collection tubes are typically used to prevent contamination and ensure accurate results.
Collection
The blood draw takes just a few minutes and is performed by trained phlebotomists using sterile techniques. The sample is then processed and analyzed using specialized laboratory equipment.
Turnaround
Results are typically available within 3-7 business days from the time the sample is received at the laboratory.
Understanding your results
Results are reported in micrograms per liter (μg/L). Reference ranges for serum chromium can vary between laboratories and depend on the analytical method used. Because chromium circulates in very low concentrations and can be affected by contamination during sample collection, proper specimen handling is important for accurate results. Healthcare providers interpret chromium levels alongside glucose and insulin measurements, dietary history, and clinical symptoms to determine whether chromium status may be contributing to metabolic concerns.
| Population | Reference Range | Notes |
|---|---|---|
| Adults | ≤ 1.4 µg/L (26.92 nmol/L) | Normal serum chromium levels for healthy adults |
Reference ranges may vary by laboratory and individual factors. Results should be interpreted by a healthcare provider in the context of your overall health.
What does a “Low” result mean?
Low chromium levels are uncommon in healthy populations consuming a balanced diet. When deficiency does occur, it is typically associated with long-term intravenous nutrition without adequate chromium supplementation. Symptoms of chromium deficiency may include weight loss, confusion, impaired coordination, and a reduced response to sugar (glucose) in blood, increasing the risk of diabetes. However, dietary chromium deficiency has not been observed in humans consuming normal diets.
What does a “High” result mean?
Elevated chromium levels may indicate exposure from occupational sources, environmental contamination, or wear from metal-on-metal orthopedic implants. Serum chromium levels can be significantly higher in patients with metal-on-metal total hip replacement implants than in control patients without metal implants. High levels may also result from specimen contamination during collection. In cases of true chromium toxicity, symptoms may include skin irritation, respiratory issues, or gastrointestinal problems, though these are rare with typical exposures.
Privacy & confidentiality
Your chromium test results are completely confidential and protected under HIPAA regulations. Results are not shared with insurance companies, will not appear on insurance explanation of benefits, and are not added to your personal medical record without your consent.
Frequently asked questions
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Last reviewed: April 2026
CPT Code: 82495
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
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