GI Pathogen Panel (Stool)
A comprehensive stool test that detects 15 common bacterial, viral, and parasitic pathogens that cause gastrointestinal infections and diarrhea.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
What this test measures
The GI Pathogen Panel uses molecular testing (nucleic acid amplification) to simultaneously screen a stool sample for the genetic material of approximately 15 common gastrointestinal pathogens, spanning bacteria, viruses, and parasites. This approach identifies infections by detecting the DNA or RNA of each organism directly, rather than relying on older culture-based methods that require growing bacteria in a laboratory over several days.
The molecular approach offers several advantages over traditional stool culture. It produces results in hours rather than days, it can detect organisms that are difficult or impossible to grow in culture, and it can identify coinfections (multiple pathogens causing illness simultaneously), which are more common than many people realize. The panel is ordered for individuals experiencing gastrointestinal symptoms such as diarrhea, abdominal pain, nausea, vomiting, or fever where an infectious cause is suspected. By rapidly identifying the specific pathogen responsible, the test helps healthcare providers select the most appropriate treatment rather than relying on empiric therapy.
What's included
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Individuals experiencing persistent diarrhea lasting more than a few days, especially when accompanied by fever, abdominal cramping, or blood in stool.
- Those with recent travel history who develop gastrointestinal symptoms, as travel-related infections may be caused by pathogens not commonly found in their home region.
- Patients with severe dehydration or concerning symptoms that require rapid identification of the causative pathogen to guide appropriate treatment decisions.
- Immunocompromised individuals who are at higher risk for severe complications from gastrointestinal infections and may require prompt diagnosis and treatment.
- People who have been exposed to potential sources of contamination, such as contaminated food or water, or during outbreaks in communal settings like nursing homes or daycare centers.
- Healthcare workers or food handlers who need to confirm they are free of infectious pathogens before returning to work in environments where transmission risk is high.
What to expect
Preparation
No special preparation is required for this test. Individuals should collect a fresh stool sample and avoid contaminating it with urine or water.
Sample Type
A small amount of fresh stool is collected in a special transport container provided by the laboratory. The sample should be collected within 2 hours or preserved in the provided transport medium.
Collection
The stool sample can typically be collected at home and transported to a laboratory location. No doctor visit is required for sample collection, making the process convenient and accessible.
Turnaround
Results are typically available within 1-3 business days, which is significantly faster than traditional stool culture methods that may take 3-5 days or longer.
Understanding your results
Results are reported qualitatively for each pathogen as either "Detected" (positive) or "Not Detected" (negative). A detected result means that the genetic material of a specific pathogen was found in the stool sample, strongly supporting an infectious diagnosis with that organism. A not-detected result means that particular pathogen was not identified, though it does not entirely exclude infection if the organism was present at very low levels or if the pathogen causing symptoms is not included in the panel. Multiple pathogens can be detected simultaneously, which may be clinically significant since coinfections can affect treatment decisions. Healthcare providers interpret results alongside symptoms, travel history, dietary exposure, and clinical presentation.
| Population | Reference Range | Notes |
|---|---|---|
| All ages | Not Detected | Normal result indicates no pathogenic organisms were detected in the stool sample |
Reference ranges may vary by laboratory and individual factors. Results should be interpreted by a healthcare provider in the context of your overall health.
What does a “Low” result mean?
A negative result means that the microbes tested were not detected and the person's signs and symptoms may be caused by a condition other than an infection or a pathogen that was not tested for. Microbes are shed into the stool intermittently. A negative result may mean that the microbe causing the person's infection was not present in the stool at the time the sample was collected. A negative result should not rule out infection in patients with a high pretest probability for gastrointestinal infection. The assay does not test for all potential infectious agents of diarrheal disease.
What does a “High” result mean?
A positive result for any pathogen indicates the presence of that specific microorganism in the stool sample and may suggest it is contributing to gastrointestinal symptoms. Multiplex GPPs consistently detect multiple targets more frequently than conventional testing. One study of 709 samples found multiple pathogens in 16.4% of samples using the BioFire GIP versus 1% after conventional testing. The detection of multiple pathogens does not necessarily mean all are causing illness, as some individuals may carry certain organisms without symptoms.
Privacy & confidentiality
Your GI pathogen panel results are completely confidential and protected under HIPAA privacy regulations. Results are not shared with your personal physician unless you specifically request it, will not be added to your medical records, and will not appear on insurance explanation of benefits statements since this is direct-pay testing.
Frequently asked questions
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View TestLast reviewed: April 2026
CPT Code: 87507
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
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