Question 1

Can I get chickenpox if I test positive for varicella immunity?

Accepted Answer

A positive varicella IgG test typically indicates strong immunity to chickenpox, making reinfection very unlikely. However, the virus can remain dormant in nerve cells and may reactivate later in life as shingles (herpes zoster), which is a different condition from chickenpox. Most people with positive immunity tests are protected against getting chickenpox again.

Question 2

How long does varicella immunity last after vaccination?

Accepted Answer

Varicella immunity from vaccination can last many years, often decades, though antibody levels may decline over time in some individuals. The CDC notes that commercial varicella IgG tests may not be sensitive enough to detect all vaccine-induced immunity, so negative results don't necessarily mean lack of protection. Most people who received the varicella vaccine maintain protection against chickenpox throughout their lives.

Question 3

What should I do if my varicella immunity test is negative?

Accepted Answer

If the test shows negative immunity, individuals who are eligible should consider getting the varicella (chickenpox) vaccine, especially if they work in healthcare settings, are planning pregnancy, or are at higher risk of exposure. Healthcare providers can recommend the appropriate vaccination schedule based on individual circumstances. It's particularly important for adults to establish immunity, as chickenpox tends to be more severe in adults than children.

Question 4

Is this test accurate for people who received the varicella vaccine?

Accepted Answer

Commercial varicella IgG tests are designed primarily to detect immunity from natural infection and may not be sensitive enough to detect all vaccine-induced immunity. The CDC states that routine testing for varicella immunity following vaccination is unnecessary because available assays may not detect all seroconversions after vaccination. However, the test can still be useful in certain situations where documentation of immunity is required.

Question 5

When is the best time to get tested for varicella immunity?

Accepted Answer

Testing can be done at any time if individuals need to document immunity status for work, school, pregnancy planning, or other requirements. However, if someone has recently been exposed to chickenpox and immunity status is unknown, testing should ideally be done as soon as possible. For those who have recently received the varicella vaccine, waiting several weeks allows time for antibodies to develop, though vaccine-induced immunity may not always be detected by standard tests.

Varicella (Chickenpox) Immunity