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Hormones

Growth Hormone (GH)

A blood test that measures growth hormone levels to assess pituitary function and diagnose growth hormone deficiency or excess.


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Blood Fasting required
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What this test measures

Growth hormone (GH), also called somatotropin, is produced by the pituitary gland and drives growth and development in children by stimulating the liver to produce insulin-like growth factor 1 (IGF-1). After the growth plates in bones fuse and adult height is reached, GH continues to play important roles in maintaining body composition, supporting muscle and bone integrity, regulating metabolism, and helping manage blood glucose levels.

The pituitary gland does not release GH at a steady rate. Instead, it secretes the hormone in short bursts throughout the day and night, with the largest pulses typically occurring during deep sleep. This pulsatile secretion pattern means that a single random blood draw may catch a peak, a trough, or anything in between, making isolated GH measurements difficult to interpret on their own. For this reason, GH testing is often paired with IGF-1 measurement, which remains far more stable throughout the day and provides a reliable reflection of average GH activity over time. In some cases, specialized stimulation or suppression tests are used to evaluate GH function more definitively.

Who should consider this test

You might consider this test if you are experiencing any of the following:

  • Individuals experiencing unexplained fatigue, decreased muscle mass, or changes in body composition, as these symptoms may be associated with growth hormone deficiency in adults.
  • Those with concerns about pituitary function, particularly individuals who have had brain surgery, radiation therapy, or head trauma that could affect the pituitary gland.
  • Patients with a family history of pituitary disorders or those who have been diagnosed with other hormone deficiencies that may indicate broader pituitary dysfunction.
  • Individuals being evaluated for potential acromegaly or gigantism, conditions associated with excessive growth hormone production that can cause abnormal growth patterns.
  • Adults with unexplained changes in bone strength, cardiovascular risk factors, or cholesterol levels, as growth hormone plays a role in bone metabolism and cardiovascular health.

What to expect

Preparation

Fasting for 8-12 hours before the test is recommended. Complete rest for at least 30 minutes before blood collection is required to minimize stress-related hormone fluctuations. Inform the healthcare provider about any medications, especially biotin supplements, which should be discontinued 72 hours before testing.

Sample Type

A simple blood draw from a vein in the arm, similar to other routine blood tests. The sample will be collected in a specialized tube and processed in the laboratory.

Collection

The blood collection takes only a few minutes and is performed by trained phlebotomists at the lab location. No special equipment or extended monitoring is required for this basic GH measurement.

Turnaround

Results are typically available within 1-3 business days after the sample reaches the laboratory.

Understanding your results

Because GH is released in pulses, a single random measurement can vary widely and is rarely sufficient on its own to diagnose a growth hormone disorder. A low reading may simply reflect a trough between secretion bursts rather than true deficiency. Healthcare providers interpret GH results alongside IGF-1 levels, clinical symptoms, growth data (in children), and sometimes the results of formal stimulation or suppression tests to arrive at an accurate assessment of pituitary function and growth hormone status.

PopulationReference RangeNotes
Adult Males0.4-10 ng/mL (18-44 pmol/L)Normal random levels for healthy adult men
Adult Females1-14 ng/mL (44-616 pmol/L)Normal random levels for healthy adult women
Children10-50 ng/mL (440-2200 pmol/L)Normal random levels for children and adolescents

Reference ranges may vary by laboratory and individual factors. Results should be interpreted by a healthcare provider in the context of your overall health.

What does a “Low” result mean?

Low growth hormone levels may be associated with growth hormone deficiency, which can cause slow growth rates in children and symptoms such as fatigue, decreased muscle mass, changes in cholesterol levels, and reduced bone strength in adults. In children, insufficient GH secretion can lead to impaired linear growth and may cause delayed sexual maturity in adolescents. However, because growth hormone is released in pulses, low random levels may also represent normal physiological patterns and require confirmation through stimulation testing.

What does a “High” result mean?

Elevated growth hormone levels may indicate the possibility of gigantism in children or acromegaly in adults, conditions often caused by pituitary adenomas. In children, this can lead to excessive growth and very tall stature, while in adults it may cause enlargement of hands, feet, and facial features. Elevated levels may also be found in certain nutritional disturbances such as anorexia, starvation, or chronic liver or kidney disease. Confirmation of growth hormone excess typically requires additional suppression testing.

Privacy & confidentiality

Your growth hormone test results are completely confidential and protected under HIPAA regulations. Results will not be shared with your personal physician unless you specifically request it, will not be added to your medical records, and will not appear on insurance explanation of benefits. Access your secure results online with complete privacy.

Frequently asked questions

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Last reviewed: April 2026

CPT Code: 83003

This test may not be available in: NY, NJ, RI

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