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Hormones

Erectile Dysfunction Test Panel


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This comprehensive ED panel is exclusively available through Quest Diagnostics and includes specialized biomarkers not offered in LabCorp's standard testing menu.

Blood Fasting required
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What this test measures

This panel evaluates the hormonal, metabolic, and cardiovascular factors most commonly associated with erectile dysfunction. The tests include morning total testosterone (with free testosterone and SHBG when indicated), pituitary hormones (LH and FSH), prolactin, thyroid function markers (TSH and free T4), diabetes indicators (fasting glucose and HbA1c), a lipid panel, and general health markers.

Erectile dysfunction is frequently a symptom of an underlying condition rather than a standalone diagnosis. Hormonal insufficiency (low testosterone, elevated prolactin, or thyroid dysfunction), insulin resistance, uncontrolled blood sugar, and unfavorable lipid profiles can all impair erectile function through different mechanisms. Early cardiovascular changes, in particular, often manifest as erectile difficulty before progressing to more overt cardiovascular disease. By screening across these interconnected systems, the panel helps identify reversible or treatable contributors that might otherwise go undetected.

What's included

50+ health and hormone markers including testosterone, thyroid, metabolic, and cardiovascular biomarkers

Who should consider this test

You might consider this test if you are experiencing any of the following:

  • Men experiencing persistent difficulty achieving or maintaining erections firm enough for satisfying sexual activity
  • Those with decreased libido, reduced energy levels, or changes in mood that may indicate hormonal imbalances
  • Men concerned about underlying health conditions like diabetes, heart disease, or thyroid disorders that can affect sexual function
  • Those who want to understand whether their erectile difficulties have a medical cause rather than psychological factors alone
  • Men seeking a comprehensive health assessment before considering erectile dysfunction treatments
  • Those who prefer private, confidential testing without discussing sensitive sexual health issues with their primary care provider

What to expect

Preparation

Fast for 8-12 hours before your test and schedule your appointment for the morning, ideally before 10 AM, as hormone levels like testosterone follow a daily rhythm and are most reliably measured in the morning. Avoid strenuous exercise and heavy alcohol intake in the 24 hours before testing.

Sample Type

A standard blood draw from a vein in your arm, typically taking just a few minutes to collect the necessary sample for all biomarkers in the panel.

Collection

Visit any Quest Diagnostics location with your test order. Present a valid ID, have your blood drawn by a trained phlebotomist, and you're done - no appointment needed at most locations.

Turnaround

Results are typically available within 1-3 business days and will be delivered securely through your patient portal.

Understanding your results

This panel identifies potential underlying causes of erectile dysfunction rather than diagnosing ED itself, which remains a clinical determination based on symptoms and history. Results span multiple biomarkers, each with its own reference range that may vary between laboratories. Healthcare providers evaluate the full set of findings together, looking for patterns (for example, low testosterone combined with elevated prolactin, or rising HbA1c alongside an unfavorable lipid profile) that point toward a specific treatable cause. Individual markers are interpreted within the broader clinical context of symptoms, age, and overall health.

PopulationReference RangeNotes
Adult men (total testosterone)264-916 ng/dLMorning levels recommended; varies by age and lab methodology
Adult men (free testosterone)66-309 pg/mLCalculated or measured; reflects bioavailable testosterone
Adult men (TSH)0.4-4.5 mIU/LThyroid stimulating hormone; varies slightly by lab
Adults (HbA1c)<5.7%Normal; 5.7-6.4% indicates prediabetes
Adults (total cholesterol)<200 mg/dLDesirable level for cardiovascular health

Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.

What does a “Low” result mean?

Low testosterone levels can result in reduced sex drive, weaker erections, and lower energy levels, as testosterone plays a major role in libido, erectile function, and overall sexual performance. Low thyroid hormone levels (hypothyroidism) can contribute to erectile dysfunction, low libido, and depression. Low levels of other biomarkers may also indicate underlying health conditions affecting sexual function.

What does a “High” result mean?

Elevated results may indicate various conditions: high cholesterol can lead to restricted blood flow making erections difficult, high blood sugar may signal diabetes or insulin resistance that can damage nerves and blood vessels, and elevated thyroid markers can affect libido and sexual performance. High TSH levels may indicate hypothyroidism, which has been associated with erectile difficulties.

Privacy & confidentiality

Your results are delivered confidentially through a secure patient portal and are not shared with employers, insurance companies, or entered into your permanent medical record unless you choose to share them with your healthcare provider. All testing is conducted with complete discretion and privacy protection.

Frequently asked questions

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Last reviewed: April 2026

CPT Code: Multiple

This test may not be available in: NY, NJ, RI

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