Does this panel diagnose IBD?

No; it provides supporting markers and helps differentiate subtypes, but diagnosis relies on endoscopy, biopsy, and clinical context.

Is this a substitute for a colonoscopy?

No. It does not replace endoscopic or histologic evaluation.

What do ANCA and ASCA suggest?

Sourced material associates ANCA more with ulcerative colitis and ASCA more with Crohn disease, as probabilities that shift likelihood rather than confirm a diagnosis.

Can results be normal and I still have IBD?

Yes; negative markers do not exclude IBD.

Autoimmune and Inflammatory

Inflammatory Bowel Disease (IBD) Differentiation Panel

A blood panel of antibody markers used to help distinguish ulcerative colitis from Crohn disease as part of a broader workup.