STD Panel — Basic (4 Tests)
A comprehensive screening panel that tests for the four most common sexually transmitted infections using blood and urine samples, with no doctor visit required.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
What this test measures
This panel screens for four of the most common sexually transmitted infections using two sample types. A blood draw tests for HIV antibodies and antigens as well as syphilis antibodies, while a urine sample is analyzed using molecular testing to detect chlamydia and gonorrhea. The combination covers bacterial and viral infections that are frequently asymptomatic, meaning many people carry them without experiencing noticeable symptoms.
Chlamydia, gonorrhea, and syphilis are bacterial infections that respond well to antibiotic treatment, especially when identified early. HIV, while not curable, is a manageable condition with modern antiretroviral therapy. Early detection across all four infections reduces the risk of complications, prevents unknowing transmission to partners, and opens the door to prompt treatment. The panel uses highly sensitive testing methods capable of detecting infections within their respective window periods, providing dependable results for informed health decisions.
What's included
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Sexually active individuals under 25, as medical experts recommend annual screening for this age group due to higher infection rates
- People with new sexual partners, multiple partners, or partners who may have other sexual relationships
- Anyone who has had unprotected sex or inconsistent condom use with partners of unknown STI status
- Individuals entering new relationships who want comprehensive baseline testing for peace of mind
- People experiencing symptoms such as unusual discharge, burning during urination, or genital discomfort
- Those who want routine health maintenance screening or have potential exposure concerns
What to expect
Preparation
No fasting is required for this test. Avoid urinating for at least 1 hour before your appointment to ensure adequate urine concentration for accurate results. If taking biotin supplements, stop consumption at least 72 hours before testing as it may interfere with blood test results.
Sample Type
A healthcare professional will draw a small blood sample from your arm using a thin needle, which takes just a few minutes. You'll also provide a urine sample by collecting the first part of your urine stream in a sterile cup.
Collection
Simply walk into any Quest Diagnostics location with your lab order. Bring a valid photo ID and your confirmation number. The entire process typically takes 15-20 minutes, and no appointment is necessary at most locations.
Turnaround
Results are typically available within 1-3 business days and will be delivered securely through your online portal
Understanding your results
Results for each infection are reported as either "Detected" or "Not Detected" (or "Reactive" / "Non-Reactive" for blood-based tests). If an initial HIV or syphilis screening result is reactive, the laboratory automatically performs confirmatory testing before finalizing the report. Chlamydia and gonorrhea are detected through molecular methods that identify bacterial genetic material with sensitivity exceeding 95%. Each result is accompanied by interpretive information specific to the testing methodology. A negative result provides reassurance, while a positive result identifies an infection that, in most cases, can be treated effectively and promptly.
| Population | Reference Range | Notes |
|---|---|---|
| Chlamydia | Not Detected | Molecular testing detects bacterial DNA; any detection indicates active infection |
| Gonorrhea | Not Detected | Molecular testing detects bacterial DNA; any detection indicates active infection |
| Syphilis | Non-Reactive | Blood test detects antibodies; reactive results require confirmatory testing |
| HIV 1 & 2 | Non-Reactive | Blood test detects antibodies and antigens; reactive results require confirmatory testing |
Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.
What does a “Low” result mean?
'Not Detected' or 'Non-Reactive' results indicate no evidence of current infection was found. However, it's important to remember that different infections have different window periods, and very recent exposures may not yet be detectable.
What does a “High” result mean?
A 'Detected' result for chlamydia or gonorrhea (molecular testing) typically indicates an active infection, since these tests detect bacterial DNA that should not be present otherwise. A 'Reactive' result on the syphilis blood test is more nuanced: syphilis screening detects antibodies, which can remain positive long after a prior infection has been successfully treated, so a reactive result may reflect a current infection, a past treated infection, or, less commonly, a false positive. Reactive screening results are routinely followed by confirmatory testing (typically a treponemal-specific test alongside the initial non-treponemal screen) to clarify the picture, and clinical history is essential for interpretation. Bacterial infections like chlamydia, gonorrhea, and active syphilis respond well to antibiotic treatment, especially when identified early. HIV is a manageable condition with proper medical care and antiretroviral therapy. Any positive or reactive result should be discussed with a healthcare provider to confirm interpretation and determine appropriate next steps.
Privacy & confidentiality
Your test results are delivered confidentially through a secure online portal and are never shared with employers, insurance companies, or anyone else without your explicit consent. Many testing facilities provide completely confidential services, and your privacy is protected under federal healthcare privacy laws throughout the entire testing process.
Frequently asked questions
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Read ArticleLast reviewed: April 10, 2026
CPT Code: 87491, 87591, 86592, 87389
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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LevelPanel has no business or affiliate relationship with Quest or LabCorp. These links are provided as a public service.
Lab testing services linked from this site are not available to residents of Alaska, Arizona, or Hawaii, unless otherwise noted on the lab's own website.
This publication is not intended to solicit the purchase of laboratory testing from any individual consumer.
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